Indian Journal of Dental Sciences

REVIEW ARTICLE
Year
: 2017  |  Volume : 9  |  Issue : 5  |  Page : 49--52

Platelet-rich fibrin or platelet-rich plasma – which one is better? an opinion


Shweta Bansal, Arun Garg, Richa Khurana, Parul Chhabra 
 Department of Periodontics, JCD Dental College and Hospital, Sirsa, Haryana, India

Correspondence Address:
Shweta Bansal
Department of Periodontics, JCD Dental College and Hospital, Sirsa, Haryana
India

The healing of hard and soft tissue in mediated by a wide range of intracellular and extracellular events that are regulated by signaling proteins. Platelets can play a crucial role in periodontal regeneration as they are the reservoirs of growth factors and cytokines which are the key factors for regeneration of bone and maturation of soft tissue. Platelet-rich plasma (PRP) is first generation platelet concentrate. However, the short duration of cytokine release and its poor mechanical properties have resulted in search of new material. Platelet-rich fibrin (PRF) is a natural fibrin-based biomaterial prepared from an anticoagulant-free blood harvest without any artificial biochemical modification (no bovine thrombin is required) that allows obtaining fibrin membranes enriched with platelets and growth factors. The slow polymerization during centrifugation, fibrin-based structure, ease of preparation, minimal expense makes PRF somewhat superior in some aspect to PRP.


How to cite this article:
Bansal S, Garg A, Khurana R, Chhabra P. Platelet-rich fibrin or platelet-rich plasma – which one is better? an opinion.Indian J Dent Sci 2017;9:49-52


How to cite this URL:
Bansal S, Garg A, Khurana R, Chhabra P. Platelet-rich fibrin or platelet-rich plasma – which one is better? an opinion. Indian J Dent Sci [serial online] 2017 [cited 2022 May 16 ];9:49-52
Available from: http://www.ijds.in/article.asp?issn=0976-4003;year=2017;volume=9;issue=5;spage=49;epage=52;aulast=Bansal;type=0