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Year : 2022  |  Volume : 14  |  Issue : 1  |  Page : 51-52

Calpain and oral cancer – A novel approach to detect cancer cell invasion

1 Department of Oral and Maxillofacial Pathology, Haldia Institute of Dental Sciences and Research, Haldia, West Bengal, India
2 Department of Dentistry, Burdwan Medical College and Hospital, Burdwan, West Bengal, India

Correspondence Address:
Sayani Shome
19/U 6, Gitabitan Apartment, Dumdum Road, Kolkata - 700 030, West Bengal
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijds.ijds_77_21

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Calpain is a Ca2+ dependent non-lysosomal cytosolic and mitochondrial cysteine protease found in tissue and organ specific manner in human being and in other mammals. It is observed to be an initiator for cancer cell propagation and invasion in Oral Squamous Cell Carcinoma (OSCC) and also a regulator of apoptosis. A concised review on this novice molecule is re-explored based on previous and ongoing studies in the following article.

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