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CASE REPORT
Year : 2022  |  Volume : 14  |  Issue : 1  |  Page : 35-39

Primitive neuroectodermal tumor of maxilla in a 4-year-old child: A rare case report with update on molecular pathogenesis


1 Department of Oral & Maxillofacial Surgery, School of Dental Sciences, Sharda University, Greater Noida, Uttar Pradesh, India
2 Department of Oral Pathology and Microbiology, School of Dental Sciences, Sharda University, Greater Noida, Uttar Pradesh, India
3 Pedodontist, Cosmozone Dental and Implant Clinic, Greater Noida, Uttar Pradesh, India

Correspondence Address:
Mithilesh Narayan Mishra
Department of Oral Pathology and Microbiology, School of Dental Sciences, Sharda University, Knowledge Park III, Gautam Buddha Nagar, Greater Noida - 201 308, Uttar Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/IJDS.IJDS_3_21

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Primitive neuroectodermal tumor (PNET) belongs to the class of malignant round cell tumor. PNETs show varying degree of neuroectodermal differentiation. They are one of the most common tumors of childhood occurring in bone and also within soft tissues. Light microscopy with the aid of immunohistochemical stains was suitable for the diagnosis. Immunohistochemistry plays a pivotal role in differentiating this tumor entity. The EWSR1-FLI1 fusion is present only in PNET cells and codes for oncogenic protein. In this article, we present a case of maxillary swelling in a 4-year-old girl child who was diagnosed with PNET. We have highlighted the challenges of diagnosing the round cell tumors.


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