• Users Online: 339
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2021  |  Volume : 13  |  Issue : 1  |  Page : 6-11

The role of decalcified freeze-dried bone allografts in the healing of postoperative osseous defects resulting from cyst enucleation: A pilot study


1 Department of Oral and Maxillofacial Surgery, Ahmedabad Dental College and Hospital, Ahmedabad, Gujarat, India
2 Department of Clinical Pharmacology, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India

Correspondence Address:
Tejashvini Joshi
Department of Oral and Maxillofacial Surgery, Ahmedabad Dental College and Hospital, Ahmedabad - 382 115, Gujarat
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/IJDS.IJDS_73_20

Rights and Permissions

Background: We performed this pilot study to evaluate the osteoinductive potential of decalcified freeze-dried bone allografts (DFDBA) in the healing of postsurgical osseous defects after cyst enucleation through radiographic bone density monitoring over a 6-month period. Materials and Methods: Patients aged between 18 and 70 years of either gender with noninfected odontogenic or nonodontogenic cystic jaw lesions measuring 1–5 cm in size were enrolled and randomly assigned to study group or control group. The study group patients were filled with DFDBA graft in bony defects resulting from the enucleation of the cysts, whereas no filling material was used in the control group. Sutures were removed on the 7th postoperative day and healing was assessed. Further follow-up visits were done at 1, 3, and 6 months. Bone densities were recorded with grayscale histogram using Adobe Photoshop (version CS 5.1) and compared across all follow-ups. Results: A total of 20 patients were enrolled in the study. Both the groups were balanced in terms of the baseline (preoperative) characteristics. There was a significant increase in bone density in the study group as compared to the control group at months 1, 3, and 6 after the surgery. There was an overall percentage increase in bone density (postoperative density as reference) at months 1, 3, and 6 in the study and control groups. However, the increase was significantly greater in the study group as compared to the control group at month 3 and month 6, whereas there was no difference between both the groups at month 1. Conclusion: Our findings suggest the osteoinductive potential of DFDBA in the healing of osseous defects resulting from the enucleation of cysts.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed850    
    Printed14    
    Emailed0    
    PDF Downloaded118    
    Comments [Add]    

Recommend this journal